Evaluate and treat gastro dmg. Animal studies have demonstrated that supplementary intake of betaine had a 2- to 5-fold increase in SAM concentrations. Betaine may influence neurological function indirectly via 5-adenosylmethionine synthesis. Sourceis in available in powdered form, and is found in many over-the-counter preparations in health food stores.NOTE: An inexpensive variety is Betaine which acts as a stomach acidifier and is not practical due to stomach irritation at the doses required to enhance methylation metabolism. Hyland et al reported increased SAM concentrations to near normal in a patient suffering from 5,10-methylenetetrahydrofolate reductase (an enzyme involved in the regeneration of ) deficiency where initial SAM concentration were undetectable.Methylation reactions and how they relate to the prevention of many diseases such as cancer, heart disease, disease and neurological disorders are a growing area of interest for researchers.
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